Bruce P Bean Selected Research

QX-314

10/2021	Inhibition of inflammatory pain and cough by a novel charged sodium channel blocker.
7/2015	Silencing Nociceptor Neurons Reduces Allergic Airway Inflammation.
7/2010	Selectively targeting pain in the trigeminal system.
10/2007	Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers.

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Bruce P Bean Research Topics

Disease

12	Pain (Aches) 01/2022 - 10/2007
4	Inflammation (Inflammations) 10/2021 - 12/2008
2	Chronic Pain 11/2021 - 08/2017
2	Epilepsy (Aura) 01/2021 - 01/2010
2	Asthma (Bronchial Asthma) 11/2019 - 07/2015
2	Neuroblastoma 06/2012 - 08/2011
1	Edema (Dropsy) 01/2022
1	Anthrax 01/2022
1	Burns 10/2021
1	Cough 10/2021
1	Surgical Wound 10/2021
1	Cerebellar Ataxia (Dysmetria) 01/2021
1	Wounds and Injuries (Trauma) 11/2019
1	Neurogenic Inflammation 11/2019
1	Sarcoma (Soft Tissue Sarcoma) 04/2014
1	Spinal Cord Injuries (Spinal Cord Injury) 08/2011
1	Huntington Disease (Huntington's Disease) 08/2011
1	Channelopathies 01/2010
1	Myotonia 01/2010
1	Paralysis (Palsy) 01/2010
1	Hypersensitivity (Allergy) 12/2008

Drug/Important Bio-Agent (IBA)

4	QX-314IBA 10/2021 - 10/2007
3	Analgesics (Analgesic Drugs)IBA 11/2021 - 11/2019
3	Sodium Channel BlockersIBA 10/2021 - 10/2007
3	Lidocaine (Xylocaine)FDA LinkGeneric 10/2021 - 10/2007
3	SodiumIBA 11/2019 - 08/2011
3	Capsaicin (Zostrix)FDA Link 07/2015 - 10/2007
2	OvalbuminIBA 10/2021 - 07/2015
2	NeuropeptidesIBA 11/2019 - 07/2015
2	Ion Channels (Ion Channel)IBA 08/2017 - 07/2015
2	Sodium Channels (Sodium Channel)IBA 08/2011 - 01/2010
1	CarrageenanIBA 01/2022
1	Formaldehyde (Formol)FDA Link 01/2022
1	Botulinum Toxins (Botulinum Toxin)IBA 01/2022
1	Bacterial ToxinsIBA 01/2022
1	AntigensIBA 01/2022
1	Proteins (Proteins, Gene)FDA Link 01/2022
1	edema factorIBA 01/2022
1	Pharmaceutical PreparationsIBA 11/2021
1	AerosolsIBA 10/2021
1	Isoflurane FDA LinkGeneric 10/2021
1	Citric Acid (Citrate)FDA LinkGeneric 10/2021
1	CationsIBA 10/2021
1	Freund's AdjuvantIBA 10/2021
1	CannabidiolIBA 01/2021
1	Large-Conductance Calcium-Activated Potassium Channels (Maxi-K Channels)IBA 01/2021
1	Calcitonin Gene-Related PeptideIBA 11/2019
1	Calcium Channels (Calcium Channel)IBA 11/2019
1	Potassium Channels (Potassium Channel)IBA 10/2017
1	EnzymesIBA 08/2017
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 08/2017
1	Superoxide Dismutase-1IBA 04/2014
1	coomassie Brilliant BlueIBA 08/2011
1	Interleukin-1beta (Interleukin 1 beta)IBA 12/2008
1	CytokinesIBA 12/2008

Therapy/Procedure

2	Analgesia 01/2022 - 11/2019
2	Therapeutics 01/2022 - 08/2017
1	Surgical Instruments (Clip) 11/2008